Drug Interaction Knowledge Base 1.2
Front Page for the Drug Interaction Knowledge Base (DIKB)
This is the front page for the Drug Interaction Knowledge Base
(DIKB), an evidence-focused knowledge base designed to support
pharmacoepidemiology and clinical decision support. The DIKB contains
quantitative and qualitative assertions about drug mechanisms and
pharmacokinetic drug-drug interactions for over 60 drugs; primarily
psychotropics and HMG-CoA reductase inhibitors (statins).
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THE MOST RECENT PUBLICATIONS FROM THE DIKB PROJECT:
- Schneider, J., Collins, C., Hines, L., Horn, JR, Boyce, R. “Modeling Arguments in Scientific Papers.” at the 12th Annual ArgDiaP Conference: From Real Data to Argument Mining. Warsaw, Poland, May 23-24 2014. http://jodischneider.com/pubs/argdiap2014.pdf
- Schneider, J., Ciccarese, P., Clark, T., Boyce, RD. "Using the Micropublications ontology and the Open Annotation Data Model to represent evidence within a drug-drug interaction knowledge base." The 4th Workshop on Linked Science 2014— Making Sense Out of Data (LISC2014). Collocated with the 13th International Semantic Web Conference (ISWC2014). October 19th and 20th, Riva del Garda, Trentino, Italy.
FOR MORE INFORMATION ON THE GOALS AND METHODS OF THE DIKB PROJECT
PLEASE SEE THE FOLLOWING:
- A "lightning" summary of the DIKB project is available
- A more detailed presentation: Boyce-AHRQ-DDI-representation-for-CDS-Talk-2009.pdf (given at the AHRQ-sponsored Generating, Evaluating, and Implementing Evidence for Drug-Drug Interactions in Health Information Technology to Improve Patient Safety: A Multi-Stakeholder Conference
- Boyce R, Collins C, Horn J, Kalet I. Computing with evidence Part II: An
evidential approach to predicting metabolic drug-drug interactions. J Biomed
Inform. 2009 Dec;42(6):990-1003. Epub 2009 Jun 16. PubMed PMID:19539050; PubMed Central PMCID: PMC2783683.
- Boyce R, Collins C, Horn J, Kalet I. Computing with evidence Part I: A
drug-mechanism evidence taxonomy oriented toward confidence assignment. J Biomed
Inform. 2009 Dec;42(6):979-89. Epub 2009 May 10. PubMed PMID: 19435613; PubMed Central PMCID: PMC2783801.
- Boyce RD, Collins C, Horn J, Kalet I. Modeling drug mechanism knowledge using
evidence and truth maintenance. IEEE Trans Inf Technol Biomed. 2007
Jul;11(4):386-97. PubMed PMID: 17674621.
- Boyce R, Collins C, Horn J, Kalet IJ. Qualitative pharmacokinetic modeling of
drugs. AMIA Annu Symp Proc. 2005:71-5. PubMed PMID: 16779004; PubMed Central
Drug Interaction Knowledge Base (DIKB) by Richard D. Boyce is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 3.0 Unported License.
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